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Every patient is valued as an individual at Preston Dental Center. You can expect high-quality dental care at each visit because we strive for perfection every day. Patients who visit us regularly for preventive care can receive custom whitening trays, instructions, and a free whitening gel at every six-month checkup! A lifelong Carolinian, Dr. Lisa earned both her dental degree and bachelor's degree from the University of North Carolina. She has been helping improve smiles for decades. Dr. Greg earned his dental degree from the University of North Carolina.
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Special Offer New Patient Dental Exam for $85 Value of $289 Schedule today to take advantage of this offer! Maintain your great smile with high-quality, personal smile care. At Preston Dental Center in Cary, you will receive some of the best care that modern dentistry can provide. Our dentists and staff are dedicated to delivering exceptional experiences every time you and your loved ones visit our practice. A team who is equipped to handle even the most complex procedures, like smile design and full-mouth rehabilitation.
Our patients come first, and our warm, friendly dental team in Cary, NC will make sure you know it! You and your family will feel welcome every time you visit us at Preston Dental Center. We look forward to meeting you at your first appointment. In the meantime, get to know our team members. With over 30 years of experience in dentistry, Lorna loves interacting with people and helping them understand what they need. In her free time, Lorna enjoys spending time with her son, watching movies, walking, and having dinner with friends and family.
Our dental professionals provide you with outstanding oral care. Put your smile in our experienced hands so you can rest easy knowing you'll receive high-quality treatments. We feature advanced dental technology so you receive efficient and effective care. You can benefit from pain-free anesthesia, same-day crowns and veneers, digital scanners, and more.
My favorite thing about being a dentist hands-down are my patients. I get up every day and I come into this office and I look forward to seeing the same people that I have seen over and over for 30 years, okay, 31 years. But I look forward to that. I also look forward to meeting new patients, new people, because every day when I have a new patient in the practice, it's like celebration, but it's always a celebration when I see all my old familiar patients and that's the same thing for everybody in the office.
Reviews (22)
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Carlo Quagliaroli
Jun 24, 2022
Very caring and professional office. Everyone is truly attentive, caring, and human to all your needs. I had the pleasure to work with Susan and Lara, amazing people. Dr. Ike is an outstanding professional. His bedside manners are beyond kind. I will definitely recommend this office to anyone in the area. Thanks for being so great!
Carson Risser
Jun 13, 2022
I have been going to Preston Dental Center for 3 years now, seeing Dr. Ike. Everyone at the office is always helpful and friendly. Even when I needed more dental work than I expected, they reassured me that I could schedule appointments on my own time with no rush. This made the whole experience much less stressful! When I've had insurance or rescheduling questions and called the office during the week, I've always received friendly and fast help. Thank you!
Gary Marechek
Jun 11, 2022
I have been coming to Preston Dental Center now for 25 years. Dr. Greg and his wonderful staff have been absolutely the best and have taken great care of my entire family. From the girls at the front desk to the hygienists and techs in the back, everyone is extremely professional and knowledgeable and they always do their job with a smile. After all, it is your smile that matters the most to them! Thank you all for a job well done!
Diana Roberto
Jun 08, 2022
Preston Dental was recommended on a community website with positive comments and over 70 hearts. I add my heart to theirs. As a new patient I found the reception staff courteous and friendly, my dental assistant Susan made me feel at ease and listened to my concerns as she reviewed my paperwork and took an X-ray. I never felt rushed and must say this was one of the best experiences I've had in a dental practice.

The dentist listened to my concerns, took time examining my teeth and came up with an initial treatment plan with my input. The facility is beautiful and sets the tone for the visit. As an Advanced Practice Nurse and Hospital Administration I view with a critical eye my health care experiences. I highly recommend Preston Dental Center. RN, MS, MPA
J. B.
Jun 05, 2022
I went to Preston Dental Center after years of neglecting professional dental care. When I entered their office the receptionist was kind and quick - I was taken to the back for my visit promptly at my appointment time. I saw Dr. Ike and my hygienist was Susan. They were both absolutely wonderful - very caring, thorough and informative. They were also able to get me in for a second visit the same week of my new patient appointment to address my dental care needs, which was amazing and unexpected.

I had been trying to find a good dentist for weeks, if not months, who could see me in a timely manner and was having trouble doing so. I even had an office cancel my appointment I had booked a month prior, which was infuriating. Finding Preston Dental Center was a huge relief. I'm very thankful for them. They're a wonderful team!
Chrisie Lue
May 20, 2022
My husband and I have been patients of Dr Gregory Mayes since 1992. I must admit that prior to finding Dr Greg my dental experience was a white knuckle event. Dr Greg has exceptional qualifications but his most outstanding quality is his empathy for his patients. He and Dr Lisa met me on a Saturday after I had cracked a front tooth. He did a temporary fix and saw me the following week to repair it. The entire staff is a group of caring, friendly and extremely skilled professionals. It is my pleasure to recommend Preston Dental Center.
Kim Werfel
Apr 09, 2022
I have been going to the Preston Dental Center for well over 20 years. We've moved out of Cary, yet still make the trip because yes, they are that good. Friendly, kind, with state of the art equipment and expert professionalism. I recommend Dr. Greg Mayes to anyone looking for an excellent dentist you can trust.
Denis Brickley
Feb 15, 2022
This place is amazing the doctors are great. They work with you as much as they can. Financing is amazing if you need it. Are used to be scared of going to the dentist because it always hurts so much but with their technology it is virtually pain-free. This is not a big deal but I wish they had better hours.
Shea Richburg
Jan 20, 2022
Dr. Ike was WONDERFUL! I have struggled with TMJ previously and having found such an amazing doctor really was magical. I recommend this doctor and this office. The staff is so professional and caring. This dentistry is really above your average office. They incorporate the latest technology to really provide the best dental treatment to their clients. If your looking for a top notch dentist please look no further.
Janet Landis
Jan 20, 2022
I have been a patient since 1994 and cannot recommend them highly enough. I have had some complicated procedures and been very satisfied. They are on the high end of cost. But worth it to me.
Suzanne Groene
Jan 13, 2022
As a patient for many years of PDC I can only say excellent things about the entire team. From the front desk people, my hygienist Lorna to Dr Greg and Dr Lisa my care has always been beyond question, superb. They treat patients like family and you feel truly cared for not only as a patient but as a person. Their ability as practitioners is beyond question. The equipment used for patients is very up to date and is in great condition. I can recommend Preston Dental Center with all confidence!
Bob Hickey
Jan 08, 2022
I have been a patient of both Lisa and Greg on the Dr. Mayes team for over twenty years. I highly recommend this dental practice. The hygienists and front office staff are wonderful to work with.
Lucy High
Jan 01, 2022
I've been coming here for about a year now and have always had a great experience. All of the staff are excellent, definitely recommend if you're looking for a new dentist!
Tameka Pettigrew
Dec 13, 2021
Love my dentist. They take really good care of me. Staff is extremely friendly!
Monica Shea-Henderson
Dec 11, 2021
Dr. Ike is great, he fixed a long term problem with sensitivity and pain I had for years seeing another dentist. He is thorough and gentle and explains everything he does step-by-step before he proceeds. I recommend him highly.
Vasanthy Chellappa
Dec 02, 2021
Dr Greg is excellent. His staff are caring and very helpful. The facility is beautiful and very clean. Strict rules are followed for COVID protection. Parking is plentiful. Dr Greg and his staff are ready at your appointment time. Best of all - they will accommodate emergency appointments. Thank you Preston dental
Linda Fleming
May 12, 2021
Care is always excellent! You're treated like family, and the staff goes out of their way to accommodate. All are personable and knowledgeable. Now my adult children go there which speaks volumes.
Kim Gooden
May 03, 2021
Dr. Ike and the staff are exceptional! I had a new crown installed and they didn't stop until it matched perfectly. I'm so happy w my care at Preston Dental Center. I've been going for 30 years. I highly recommend them.
Donna Lippert Watson
Apr 29, 2021
Professional, personable, caring and informative. Kelly is the best hygienist. Front desk is very efficient.
Tom Flaherty
Apr 24, 2021
We have been patients of PDC for over 10 years and have been very satisfied with their services. From routine cleaning to root canals, the caring professionalism is outstanding. Highly recommended!
Joyce Werkmeister
Apr 06, 2021
Love Dr Gregg and Tiffany and Love talking with Melanie and Breck. The best staff Ever
Jennifer Tamburro
Feb 10, 2021
I cannot say enough good things about Preston Dental Center and Dr. Lisa, in particular. I started going to this practice a couple years ago after hearing so many good things about them from friends and neighbors. The practice is completely state-of-the-art, and I have never felt more comfortable with and confident in the care I'm receiving. Dr. Lisa is extraordinarily professional, kind, and reassuring, and every interaction among staff members is friendly and respectful. My only regret is that I didn't make the switch to her practice sooner!